Restylane is a crystal-clear gel that may be used for filling out facial wrinkles, facial folds, and the lips, approved for usage by the FDA in 2004. Restylane contains hyaluronic acid, which is a natural substance already present in the skin. Once injected, it works together with the body’s own hyaluronic acid to create volume. The results can be seen immediately, with the majority of patients enjoying the effects longer than six months. This may vary based on the structure of the skin, age, and lifestyle of the patient.